software

Stutter mONte Carlo Simulation - SONiCS in short, is an algorithm design to determine the genotype of a Short Tandem Repeats (STR) given a noisy input. It performs dense forward simulations of the PCR of STR from capture experiments and dermines the most probable genotype.

SONiCS performs dense forward simulations of the PCR of Short Tandem Repeats from capture experiments, calculates the likelihood of generating the provided read support (reads per allele) out of the final PCR pool and determines the most probable genotype based on the log likelihood distributions from all such simulations.